Marc Diederich Selected Research

Azacitidine (5 Azacytidine)

1/2019	Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
2/2014	Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.

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Marc Diederich Research Topics

Disease

108	Neoplasms (Cancer) 05/2024 - 10/2003
33	Leukemia 04/2023 - 10/2003
20	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 05/2024 - 01/2007
13	Inflammation (Inflammations) 01/2020 - 04/2004
11	Carcinogenesis 01/2020 - 10/2003
6	Breast Neoplasms (Breast Cancer) 01/2021 - 09/2010
6	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 03/2010
5	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2023 - 11/2015
5	Necrosis 01/2020 - 10/2003
5	Anemia 01/2019 - 08/2006
4	Myeloid Leukemia (Leukemia, Myelocytic) 05/2024 - 01/2020
3	Neoplasm Metastasis (Metastasis) 01/2018 - 03/2010
3	Lung Neoplasms (Lung Cancer) 01/2018 - 07/2013
2	Multiple Myeloma 01/2021 - 08/2006
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2019 - 02/2014
2	Lymphoma (Lymphomas) 12/2015 - 01/2014
2	Hematologic Neoplasms (Hematological Malignancy) 01/2014 - 10/2010
2	Heart Failure 05/2013 - 01/2011
2	Acute Erythroblastic Leukemia (Erythroleukemia) 03/2009 - 05/2006
1	Mitochondrial Diseases (Mitochondrial Disease) 05/2024

Drug/Important Bio-Agent (IBA)

15	CurcuminIBA 10/2015 - 10/2003
12	NF-kappa B (NF-kB)IBA 01/2017 - 10/2003
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 04/2004
9	Proteins (Proteins, Gene)FDA Link 05/2021 - 10/2003
8	DNA (Deoxyribonucleic Acid)IBA 09/2022 - 02/2011
8	AntioxidantsIBA 01/2018 - 04/2004
7	Imatinib Mesylate (Gleevec)FDA Link 05/2021 - 12/2018
7	EnzymesIBA 01/2019 - 04/2004
7	Transcription Factors (Transcription Factor)IBA 11/2014 - 10/2003
6	Glutathione Transferase (Glutathione S-Transferase)IBA 01/2014 - 10/2003
5	Biomarkers (Surrogate Marker)IBA 10/2023 - 10/2011
5	Histone Deacetylases (Histone Deacetylase)IBA 01/2020 - 09/2013
5	CytokinesIBA 01/2019 - 11/2008
5	Decitabine FDA Link 01/2019 - 02/2011
5	Cytostatic AgentsIBA 12/2018 - 07/2013
4	Cardiac GlycosidesIBA 10/2023 - 01/2011
4	Histone Deacetylase InhibitorsIBA 01/2020 - 08/2014
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 11/2015 - 01/2010
4	ChalconesIBA 09/2014 - 04/2006
3	Tyrosine Kinase InhibitorsIBA 05/2024 - 01/2020
3	bcr-abl Fusion ProteinsIBA 01/2020 - 01/2008
3	Therapeutic UsesIBA 01/2020 - 12/2015
3	Histones (Histone)IBA 02/2018 - 09/2013
3	Sirtuin 1IBA 02/2018 - 11/2014
3	Antineoplastic Agents (Antineoplastics)IBA 01/2017 - 01/2016
3	FlavonoidsIBA 07/2016 - 09/2014
3	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2014 - 04/2004
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2014 - 10/2003
3	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 11/2011 - 12/2010
3	Glutathione (Reduced Glutathione)IBA 02/2009 - 09/2004
2	VaccinesIBA 05/2024 - 01/2019
2	CalciumIBA 05/2024 - 01/2018
2	quinolineIBA 09/2022 - 01/2019
2	indoleIBA 11/2021 - 05/2021
2	CaspasesIBA 10/2020 - 02/2014
2	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2020 - 06/2014
2	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 01/2015
2	MethyltransferasesIBA 01/2019 - 02/2014
2	CoumarinsIBA 01/2019 - 01/2018
2	Azacitidine (5 Azacytidine)FDA Link 01/2019 - 02/2014
2	Hormones (Hormone)IBA 06/2018 - 05/2015
2	AlkaloidsIBA 02/2018 - 04/2016
2	TubulinIBA 02/2018 - 12/2017
2	Adenosine Triphosphatases (ATPase)IBA 11/2017 - 05/2013
2	LactonesIBA 01/2017 - 04/2006
2	cyclohexanoneIBA 01/2017 - 09/2010
2	Androgen Receptors (Androgen Receptor)IBA 01/2016 - 03/2010
2	PolyphenolsIBA 10/2015 - 10/2013
2	Celecoxib (Celebrex)FDA Link 10/2015 - 11/2011
2	ThiazolidinedionesIBA 05/2015 - 11/2014
2	Apoptosis Regulatory ProteinsIBA 01/2015 - 11/2012
2	aclacinomycinsIBA 11/2014 - 03/2009
2	Erythropoietin FDA Link 11/2014 - 07/2011
2	KetonesIBA 09/2014 - 09/2011
2	Etoposide (VP 16)FDA LinkGeneric 01/2014 - 04/2012
2	Cisplatin (Platino)FDA LinkGeneric 12/2013 - 04/2012
2	Phosphotransferases (Kinase)IBA 10/2013 - 01/2007
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 10/2013 - 04/2011
2	ChromatinIBA 11/2012 - 06/2011
2	MicroRNAs (MicroRNA)IBA 06/2012 - 10/2011
2	AndrogensIBA 06/2012 - 03/2011
2	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2012 - 03/2009
2	Sulfur Compounds (Compounds, Sulfur)IBA 03/2011 - 05/2009
2	UNBS 1450IBA 01/2011 - 07/2009
2	MelatoninIBA 12/2010 - 08/2009
1	venetoclaxIBA 10/2023
1	Immune Checkpoint InhibitorsIBA 10/2023
1	palytoxinIBA 04/2023
1	sulforaphaneIBA 12/2021
1	QuinazolinesIBA 11/2021
1	aplysinopsinIBA 05/2021
1	A-1210477IBA 05/2021
1	asciminibIBA 01/2021
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2021

Therapy/Procedure

28	Therapeutics 05/2024 - 07/2009
9	Drug Therapy (Chemotherapy) 07/2016 - 06/2005
8	Chemoprevention 03/2014 - 06/2005
6	Immunotherapy 05/2024 - 03/2010
3	Traditional Medicine (Folk Remedies) 09/2014 - 04/2006